Practical copper(I)-catalysed amidation of aldehydes.
نویسندگان
چکیده
The direct synthesis of amides by insertion into the C-H bond of aldehydes is shown to be a practical procedure through application of cheap, readily available catalysts generated in situ from copper(i) halides and pyridine.
منابع مشابه
A copper-catalysed amidation of aldehydes via N-hydroxysuccinimide ester formation.
A copper-catalysed oxidative amidation of aldehydes via N-hydroxysuccinimide ester formation is reported. The methodology employed to prepare amides directly from aldehydes has a very wide scope, is high yielding, and does not need dry conditions. This cross-coupling reaction appears to be simple and makes use of cheap, abundant and easily available reagents.
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عنوان ژورنال:
- Chemical communications
دوره 46 6 شماره
صفحات -
تاریخ انتشار 2010